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This global class is a joint course of Florida State University (FSU) and Higher School of Economics (HSE), St Petersburg, Russia. It embraces cluster-oriented economic development strategies in a global setting. Industrial clusters are co-location of firms and workers in related industries, with Silicon Valley as a famous example. In recent years, many nations and regions have adopted cluster-promoting strategies to encourage local economic development, create jobs, boost innovation and prompt entrepreneurship. In this course, we take a project-based approach and center around cross-continental joint projects to explore effective ways of cluster development, apply comprehensive methods to track the performance of industrial clusters, and formulate policy recommendations to improve their functionality.